SPRB

Spruce Biosciences, Inc.

$46.66

-5.42%
SectorHealthcareIndustryBiotechnologyCountryUnited States

Spruce Biosciences, Inc. is a biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders. The company develops TA-ERT, a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase, which is an enzyme replacement therapy for patients with Sanfilippo Syndrome Type B. It also develops Tildacerfont for treating a highly debilitating mental disorder characterized by depressed mood with cognitive-affective and somatic changes, including anhedonia, weight alterations, and altered sleeping patterns. In addition, the company develops SPR202 for the treatment of Congenital Adrenal Hyperplasia (CAH), a chronic and potentially life-threatening rare disease with no cure. The company has a license agreement with Eli Lilly and Company to research, develop, and commercialize various pharmaceutical compounds. It also has a collaboration and license agreement with Kaken Pharmaceutical Co. Ltd.

Source: Yahoo Finance
AI summary

Price & performance

1M+5.9%
3M+1.0%
YTD-48.6%
1Y-59.6%
52-week range—
Beta1.71
Full chart and returns against a benchmark

Q-Score

42/ 100

Quality against peers; 50 is the peer median.

Growth15
Risk16
Performance76
Valuation48
Profitability47
Leverage41
Sentiment52
Every score and metric

News sentiment

Open News

Latest results · FY 2025

Revenue—
Net income-$39M
Net margin—
Historical fundamentals

Red flags in filings

1active red flag
Going-concern doubtMar 9, 2026
Filings, findings and the timeline

Revenue exposure

0%of revenue from outside the US
United States100%
Regions, segments, customers and suppliers

Valuation

SPRBIndustryP/E—89.69P/S—11.88EV/EBITDA—67.10P/B2.026.22PEG—4.02
Dividend yield0.00%
Every valuation metric